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. 2015 Jul 14;5:12025. doi: 10.1038/srep12025

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Copyright © 2015, Macmillan Publishers Limited

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Panel A (top): The process platform includes the distillation component (right box in dashed-dotted lines) and the synthesis/purification component (left, box in dotted lines) Panel B (middle): The astatine distillation component of the platform includes: a) a tube furnace, b) a quartz glass oven c) carrier gas flow, d) a vacuum pump, e) a carrier gas dryer, f) an astatine condensation capillary, g) a cryotrap, h) a reaction vial, i) astatine capture traps, and j) three-way valves. The components outlined in dashed lines are shown in detail in Fig. 5. Panel C (bottom): The astatine labelling/synthesis component of the automatic process platform includes: a) a reaction vial, b) sealed containers for reagent storage and introduction, c) a purification column, d) a syringe dispenser, e) containers for column buffers and reagents, f) a waste container, g) sterile filter option, h) a product vial, and i) three-way valves.