Table 1.
Study population characteristics at re-evaluation. Values are shown as medians and range
| All | IgG patients | IgA patients | |
|---|---|---|---|
| Number of patients |
90 |
66 |
24 |
| Age (years) |
61 (39-84) |
61 (39-84) |
64 (45-84) |
| Sex (male/female) |
42/48 |
32/34 |
10/14 |
| Total immunoglobulin – standard method (g/L) |
10.48 (1.05-54.32) |
11.48 (2.85-54.32) |
4.76 (1.05-35.49) |
| Serum free light chain ratio |
1.08 (0.0-299.0) |
1.16 (0.0-299.0) |
0.75 (0-25.8) |
| β-2-microglobulin (mg/L) |
2.34 (1.3-11.15) |
2.3 (1.3-11.15) |
2.45 (1.70-9.78) |
| Albumin (g/L) |
41.8 (16.8-69.0) |
42.15 (30.6-69.0) |
39.2 (16.8-44.9) |
| Hemoglobin (g/L) |
125 (86-179) |
125 (86-149) |
125 (101-179) |
| Thrombocytes ( × 109/L) |
187 (43-567) |
190 (43-567) |
184 (99-378) |
| Creatinine (µmol/L) |
90 (47-256) |
90 (47-172) |
77 (51-256) |
| Serum calcium (mmol/L) |
2.34 (1.82-2.86) |
2.33 (1.97-2.79) |
2.43 (1.82-2.86) |
| Lactate dehydrogenase (U/L) |
182 (79-862) |
190 (79-862) |
158 (113-264) |
| Percentage of plasma cells |
6 (0-95) |
6 (0-70) |
7.5 (0-95) |
| International Staging System stage I / II / III (No.) |
53 / 34 / 3 |
36 / 29 / 1 |
17 / 5/ 2 |
| Complete response (No.) |
23 |
15 |
8 |
| Very good partial response (No.) |
34 |
28 |
6 |
| Partial response (No.) |
10 |
8 |
2 |
| MR/SD/PD/relapse (No.) | 1 /10 / 7 / 5 | 1 / 5 / 4 / 5 | 0 / 5 / 3 / 0 |
*MR – minimal response; SD – stable disease; PD – progressive disease.