. 2015 Jul 14;5:12323. doi: 10.1038/srep12323

Table 1. A distribution analysis for changes in Ollivier-Ricci average curvature between cancer and normal tissue for all metabolic case studies.

Ricci Curvature	BRCA^M	HNSC^M	KIRP^M	LIHC^M	LUAD^M	THCA^M
Δ Average	0.0195	0.0186	0.0229	0.0035	0.0075	0.0117
p-Value	<1e-25	<1e-25	<1e-25	<1e-25	<1e-25	<1e-25
Δ 5% Left Tail	0.0059	0.0077	0.0077	0.0016	0.0022	0.0013
Δ 5% Right Tail	0.0059	0.0057	0.0059	0.0005	0.0017	0.0010

These statistics show that there exists a positive shift in the distribution signifying robustness. We also include the one tailed pair Wilcoxon signed rank test p-values to support the above statistics.