. Author manuscript; available in PMC: 2015 Jul 14.

Published in final edited form as: Eur J Prev Cardiol. 2013 Dec 16;22(3):364–372. doi: 10.1177/2047487313517576

TABLE 2.

Relative Risk (95% Confidence Interval) of Cardiovascular Mortality According to Quartile of Omega-3 Fatty Acids Intake

	Quartiles Quartile of Omega-3 Fatty Acids Intake				P for trend^*
	Q1	Q2	Q3	Q4	P for trend^*
Total omega-3 intake
Cases/person-years	1329/220747	1200/220839	1196/223184	1055/225703
Multivariate Model 1^†	1.00	0.90 (0.83-0.98)	0.93 (0.86-1.00)	0.88 (0.81-0.95)	0.006
Multivariate Model 2^‡	1.00	0.88 (0.81-0.96)	0.88 (0.80-0.97)	0.83 (0.74-0.92)	0.003
Marine omega-3 (EPA + DHA) intake
Cases/person-years	1236/219336	1233/220994	1188/225056	1123/225088
Multivariate Model 1^†	1.00	0.99 (0.92-1.08)	0.96 (0.89-1.04)	0.95 (0.88-1.03)	0.16
Multivariate Model 2^‡	1.00	0.96 (0.89-1.05)	0.90 (0.82-0.99)	0.86 (0.77-0.96)	0.004
Non-marine omega-3 (ALA) intake
Cases/person-years	1342/222500	1267/221695	1156/221955	1015/224323
Multivariate Model 1^†	1.00	0.95 (0.88-1.03)	0.89 (0.82-0.97)	0.84 (0.77-0.91)	<0.001
Multivariate Model 2^‡	1.00	0.94 (0.86-1.02)	0.87 (0.79-0.95)	0.81 (0.73-0.90)	<0.001

EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; ALA, a-linolenic acid.

Linear trend was tested by assigning to participants the median value in each quartile and assessing this as a continuous variable.

^†

Multivariate model 1 adjusted for age, sex, dialect, year of interview, educational level, body mass index, physical activity, smoking status, alcohol use, baseline history of self-reported diabetes, hypertension, coronary heart disease, stroke, and total energy.

^‡

Multivariate model 2 further adjusted for intakes of protein, dietary fiber, monounsaturated fat, saturated fat, omega-6 fatty acids, and alternate omega-3 fatty acids (in the analysis of EPA/DHA or ALA).