Table 2.

Representative gene mapping to clusters which show a change in methylation of ≥∣2%∣ or ∣0.02∣, at a FDR cutoff of 0.05.

Region ID	Gene	CpG island	Promoter associated	Effect size	Standard error	P value	FDR	CpG sites/ cluster
Conserved	VAMP5	chr2:85811340- 85811855	Yes	0.031	0.009	0.000839	0.0410	5
Conserved	CAPN2	chr1:223936342- 223937044	Yes	0.024	0.005	5.94E-06	0.00174	3
Conserved	PF4	chr4:74847528- 74847830	No	0.0933	0.0223	2.38E-05	0.00395	4
Conserved	LEP	chr7:127880750- 127881375	No	0.036	0.01	0.00045	0.0280	2
Conserved	ETFA	chr15:76603563- 76604026	Yes	−0.046	0.013	0.000387	0.0258	2
Male-specific	RUNX1	chr21:36258952- 36259472	No	−0.084	0.025	0.00082	0.0373	5
Male-specific	GABRG1	Non-CpG	No	−0.08	0.019	4.24E-05	0.00534	5
Male-specifc	MRPS25	chr3:15106459- 15106971	Yes	−0.064	0.020	0.00148	0.0497	2
Female-specific	APP	Non-CpG	No	0.043	0.013	0.00131	0.0366	4
Female-specific	LONP1	chr19:5690127- 5692213	No	0.038	0.012	0.00143	0.0391	2
Female-specific	MTERFD2	chr2:242041543- 242042026	Yes	0.021	0.003	8.73E-10	5.43E-07	7
Female-specific	HPCAL1	chr2:10442308- 10444509	Yes	−0.055	0.017	0.00111	0.0323	2
Female-specific	MAP3K6	chr1:27683277- 27683590	Yes	0.061	0.016	8.8E-05	0.00534	5
Female-specific	HIF3A	chr19:46800053- 46800603	No	0.06	0.019	0.00150	0.0405	2
Female-specific	RUNX3	chr1:25255527- 25259005	No	0.045	0.012	0.00017	0.00859	2