Table 1. MIC versus isolates resistant to ciprofloxacin, the NBTI, novobiocin and ETX0914.

Shaded areas represent ≥8-fold increase in MIC relative to susceptible strains; Boldface represents increased sensitivity.

^a,bhomologous residues by sequence analysis; ^chomologous to E88 (Fig. 3); ^dhomologous to R458 (Fig. 3); ^dsequence aligned with N475 (Fig. 3)⁹; ^emutant derived from the spontaneous resistance study with ETX0914.