Table 4.
All | Gadopentetat (Magnevist) | Gadoteracid (Dotarem) | Gadobenat (Multihance) | Gadotbutrol (Gadovist) | Gadoteridol (Prohance) | Gadodiamide (Omniscan) | Other* | |
---|---|---|---|---|---|---|---|---|
All | 45 | 20 | 5 | 3 | 9 | 2 | 3 | 3 |
Age (years, mean) | 51.9 | 50.8 | 48.2 | 68.0 | 49.6 | 38.0 | 62.0 | 56.0 |
SD | 16.5 | 18.1 | 19.0 | 4.6 | 16.1 | 14.1 | 4.0 | 13.0 |
Median | 54.0 | 54.0 | 53.0 | 69.0 | 42.0 | 38.0 | 62.0 | 56.0 |
Range | 16-77 | 16-74 | 25-69 | 63-72 | 31-77 | 28-48 | 58-66 | 43-69 |
Sex | ||||||||
Male (%) | 62.2 | 75.0 | 60.0 | 33.3 | 44.4 | 50 | 66.7 | 66.7 |
Contrast dose (ml, mean) | 20.6 | 22.5 | 24.8 | 13.7 | 13.2 | 14.3 | 20.0 | 23.0 |
SD | 8.3 | 7.5 | 8.8 | 3.2 | 4.3 | 17.0 | 8.0 | 11.5 |
Median | 20.0 | 22.5 | 28.0 | 15.0 | 14.0 | 28.0 | 20.0 | 27.0 |
Range | 7-40 | 7-36 | 10-32 | 10-16 | 10-21 | 16-40 | 12-28 | 10-32 |
Category of reaction | ||||||||
Mild | 43 | 18 | 5 | 3 | 9 | 2 | 3 | 3 |
Moderate | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Severe | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
Symptoms | ||||||||
Allergic shock | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
Cardiac arrest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Dyspnoea | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Bronchospasm | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Nausea | 10 | 3 | 0 | 1 | 2 | 0 | 2 | 2 |
Vomiting | 6 | 3 | 0 | 0 | 0 | 0 | 2 | 1 |
Warmth | 3 | 2 | 0 | 1 | 0 | 0 | 0 | 0 |
Headache | 2 | 1 | 0 | 0 | 0 | 0 | 0 | 1 |
Dizziness | 5 | 3 | 0 | 0 | 0 | 0 | 2 | 0 |
Altered taste | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Itching | 9 | 2 | 1 | 1 | 4 | 1 | 0 | 0 |
Flushing | 10 | 2 | 1 | 1 | 6 | 0 | 0 | 0 |
Chills | 2 | 1 | 0 | 0 | 1 | 0 | 0 | 0 |
Sweats | 3 | 2 | 0 | 0 | 1 | 0 | 0 | 0 |
Rash/Hives | 15 | 4 | 4 | 2 | 2 | 2 | 1 | 0 |
Swelling of eye/face | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Anxiety | 6 | 6 | 0 | 0 | 0 | 0 | 0 | 0 |
Treatment | ||||||||
Observation | 30 | 14 | 3 | 2 | 5 | 1 | 2 | 3 |
Antihistamines | 18 | 4 | 3 | 2 | 4 | 1 | 3 | 1 |
Steroids | 14 | 3 | 1 | 2 | 3 | 2 | 3 | 0 |
Adrenaline | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
*Dotarem is included in Other