Skip to main content
. Author manuscript; available in PMC: 2015 Jul 14.
Published in final edited form as: Nature. 2014 Jun 11;510(7505):407–411. doi: 10.1038/nature13444

Figure 1. Impact of genetic inactivation of p110δ on tumour growth and metastasis.

Figure 1

a, percentage of mice with visible B16 ear tumours (left) or lymph nodes metastasis (right). Photographs show B16 metastases in cervical lymph nodes and representative excised lymph nodes. b-d, primary tumour burden of the indicated tumour lines. e, 4T1 metastasis as detected by luciferase activity (left and middle panel) or histology (right panel), expressed as a percentage of the total number of tumour-bearing animals/group. f, Growth of primary 4T1 tumours. g, Survival of 4T1 tumour-bearing mice. a-f, Statistically significant differences are indicated by * (P < 0.05) or ** (P < 0.01), as determined by the non-parametric Mann-Whitney t test. Between brackets: number of mice used per experiment. Each dot represents an individual mouse.