Fig. 4.

EEP inhibits ox-LDL-induced ER stress response in RAW264.7 cells. Cells were pretreated with the indicated concentrations of EEP or PBA (5 mmol/L) in the presence of ox-LDL (100 mg/L) for 24 h, and then the protein (a) and mRNA (b) levels of ER stress markers were evaluated by Western blot and quantitative real-time PCR, respectively. Data are expressed as the mean ± SEM of at least three independent experiments. *P < 0.05, **P < 0.01 versus vehicle-treated control; ^# P < 0.05, ^## P < 0.01 versus ox-LDL treatment