Table 2.
Fluorine and deoxy CA analogs EC50 for lowering Aβ42
| |||
|---|---|---|---|
| R1 | R2 | Cmpd # | Aβ42 EC50 (nM) |
| β-F | α-H | 12 | 8906 |
| β-H | β-H | 13 | 671 |
EC50=half maximal effective concentration
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