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. 2015 Jul 14;9:244. doi: 10.3389/fnins.2015.00244

Figure 10.

Figure 10

Structural elements of steroid compounds that activate V1rj2 and V1rj3 receptors. (A) Steroid compounds that activate V1rj2 and V1rj3 receptors. The minimal concentrations of activation are indicated. (B) Molecular structures of sulfated or glucuronidated steroids that induce no or weak responses. (C) Schematic illustration of important structural elements required to activate the V1rj2 and V1rj3 receptors. The estradiol backbone (yellow) and 17-β hydroxyl group (pink) are highlighted. Structural permutations that are permissible are indicated by arrows in the right panel.