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. 2015 Jul 14;9:244. doi: 10.3389/fnins.2015.00244

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Copyright © 2015 Haga-Yamanaka, Ma and Yu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Activation of V1rj2 by E1050. (A) Examples of sigmoidal dose-response curves to E1050 in V1rj2 cells. (B) Bar graph showing the percentage of E1050 activated V1rj2 cells (n = 200). (C) Examples of bell-shaped dose- response curves to E1050 in V1rj2 cells. (D) Dose-response curves of individual cells (gray) and a sigmoidal curve (black) fitted to the average amplitude from all cells. Error bar, S.E.M. (E) Pie charts showing the number of cells exhibiting sigmoidal (S, blue), bell-shaped (B, red), and other (O, green) types of dose responses. Cells with FRC of 10⁻⁷ M are shown in gray.