Table 3.
Test on SABmark database.
| Methods On subsets | Reference-dependent (Q-score)
|
Reference-independent (TM-score)
|
||
|---|---|---|---|---|
| SABmark_TWI | SABmark_SUP | SABmark_TWI | SABmark_SUP | |
|
|
|
|||
| PROMALS | 46.2 | 71.1 | 0.413 | 0.583 |
| SFESA (O)+PROMALS | 47.3 | 71.3 | 0.416 | 0.585 |
| SFESA (O+G)+PROMALS | 48.0 | 71.8 | 0.416 | 0.585 |
| SFESA (O+G+M)+PROMALS | 47.9 | 71.9 | 0.416 | 0.586 |
| SFESA (O+G+M+S)+PROMALS | 48.1 | 72.1 | 0.416 | 0.587 |
| HHpred | 40.7 | 68.9 | 0.371 | 0.570 |
| SFESA (O)+HHpred | 40.6 | 69.0 | 0.371 | 0.570 |
| SFESA (O+G)+HHpred | 41.3 | 69.1 | 0.372 | 0.571 |
| SFESA (O+G+M)+HHpred | 41.4 | 69.6 | 0.372 | 0.571 |
| SFESA (O+G+M+S)+HHpred | 41.3 | 69.4 | 0.373 | 0.571 |
| CNFpred | 41.5 | 66.1 | 0.368 | 0.543 |
| SFESA (O)+CNFpred | 41.6 | 66.4 | 0.367 | 0.545 |
| SFESA (O+G)+CNFpred | 42.3 | 67.0 | 0.370 | 0.545 |
| SFESA (O+G+M)+CNFpred | 42.4 | 67.4 | 0.371 | 0.545 |
| SFESA (O+G+M+S)+CNFpred | 42.2 | 66.9 | 0.370 | 0.545 |
Columns 2–3 indicate the alignment Q-score based on their reference on two subsets of the SABmark benchmark: “twilight zone” and “superfamilies” respectively (Reference-dependent evaluation). Columns 4–5 indicate the average of query model’s TM-score built by Modeller on two subsets of the SABmark benchmark: “twilight zone” and “superfamilies” respectively (Reference-independent evaluation). Bold indicates the best performance in the subsection. Bold with underscore indicates the overall best performance in one column.