Table 3.
Linear regression of echocardiographic parameters on the Sokolow-Lyon index within considered BMI categories, and respective interaction analyses
| BMI (kg/m2) | Crude betaa (95 % CI) | p | p (interaction)* | Adjusted betaa,b (95 % CI) | p | p (interaction)* | |
|---|---|---|---|---|---|---|---|
| LVMI (g/m2) | <25 | 6.34 (1.58, 11.10) | 0.0092 | 4.79 (0.47, 9.11) | 0.0041 | ||
| 25–29.9 | 6.09 (1.86, 10.33) | 0.0049 | 0.0389 | 5.51 (1.75, 9.27) | 0.001 | 0.0244 | |
| ≥30 | 9.55 (3.81, 15.30) | 0.0012 | 9.24 (3.75, 14.73) | 0.001 | |||
| LVIDd (cm/m2) | <25 | 0.05 (0.00, 0.09) | 0.0384 | 0.03 (−0.01, 0.07) | 0.1306 | ||
| 25–29.9 | 0.10 (0.06, 0.13) | <0.0001 | 0.3948 | 0.08 (0.05, 0.12) | <0.0001 | 0.1280 | |
| ≥30 | 0.08 (0.04, 0.12) | 0.0002 | 0.07 (0.02, 0.11) | 0.0031 | |||
| PWTd (cm) | <25 | 0.02 (−0.01, 0.04) | 0.2255 | 0.01 (−0.01, 0.03) | 0.4774 | ||
| 25–29.9 | 0.00 (−0.02, 0.02) | 0.9225 | 0.3672 | −0.01 (−0.03, 0.01) | 0.5528 | 0.4426 | |
| ≥30 | 0.02 (−0.01, 0.04) | 0.2604 | 0.02 (−0.01, 0.04) | 0.2478 | |||
| SWTd (cm) | <25 | 0.01 (−0.01, 0.04) | 0.3217 | 0.01 (−0.01, 0.03) | 0.4411 | ||
| 25–29.9 | 0.01 (−0.02, 0.03) | 0.624 | 0.6835 | 0.00 (−0.02, 0.02) | 0.8048 | 0.9081 | |
| ≥30 | 0.01 (−0.02, 0.03) | 0.4979 | 0.01 (−0.02, 0.03) | 0.5193 |
SLI Sokolow-Lyon index, LVMI left-ventricular mass index, LVIDd left-ventricular internal diameter at end-diastole index, PWTd left-ventricular posterior wall thickness at end-diastole, SWTd septal wall thickness at end-diastole, 95 % CI 95 % confidence interval
*p-value of the multiplicative interaction of the SLI with considered BMI classes
aadjusted for sex, sport index, smoking status, NT-pro BNP, low density lipoprotein, arterial hypertension, waist-to-hip ratio, diabetes mellitus, regular intake of antiarrhythmic medication, beta blockers and digitalis glycosides
bBeta gives the increase of the respective echocardiographic parameter per mV increase of the SLI