Ref (type) | Population | Outcome, Interventions | Results and statistical analysis | Effect size | Favours |
Healing | |||||
[33]
RCT |
76 children presenting within 24 hours of injury with a previously untreated burn; 66 of whom had superficial partial-thickness burns In review [11] |
Mean healing time
7.58 days with silicone-coated nylon dressing 11.26 days with silver sulfadiazine cream |
P <0.01 RCT gave no information on methods for randomisation or allocation concealment Participants and investigators not blinded |
Effect size not calculated | silicone-coated nylon dressing |
[34]
RCT |
66 children with superficial partial-thickness burns of <15% total body surface area (TBSA) In review [11] |
Median time to full re-epithelialisation of the wound
10.5 days with silicone mesh dressing 27.6 days with silver sulfadiazine cream |
P = 0.0002 Participants and investigators not blinded |
Effect size not calculated | silicone mesh dressing |
Number of dressing changes | |||||
[11]
Systematic review |
76 children presenting within 24 hours of injury with a previously untreated burn; 66 of whom had superficial partial-thickness burns Data from 1 RCT |
Number of new dressings
3.64 with silicone-coated nylon net dressing 5.13 with silver sulfadiazine cream |
MD –1.49 95% CI –2.64 to –0.34 P <0.001 Result expected as dressings were changed every 2–3 days until complete healing was obtained, and simply reflects the longer healing period with the silver sulfadiazine cream; dressing removal was reported as easy and atraumatic RCT gave no information on methods for randomisation or allocation concealment Participants and investigators not blinded |
Effect size not calculated | silicone-coated nylon dressing |