Table 2.
Faecal concentration of individual SCFA
| Subjects (n); age | Reported measure | Acetic acid | Propionic acid | Butyric acid | Total SCFA | Unit | Reference | |
|---|---|---|---|---|---|---|---|---|
| Healthy subjects | 10; 21–34 years | Mean (sd) | 218 (99) | 72 (37) | 58·7 (54·5) | 378 (188) | μmol/g dry weight | Whelan (2005)( 236 ) |
| 20; 20–40 years | Mean (sem) | 320·3 (24·9) | 97·3 (10·5) | 93·8 (9·13) | 511·4 (41·9) | μmol/g dry weight | Boler (2011)( 111 ) | |
| 13; 23–58 years | Median (IQR) | 52·2 | 23·2 (13·6–37·3) | 36·8 (5–128) | 119·3 (64·5–197·0) | μmol/g wet weight | Lewis (1997)( 237 ) | |
| 60; 18–24 years | Mean (sem) | 198·4 (14·2) | 55·2 (4·7) | 50·5 (4·9) | 304·1 | μmol/g dry weight | Lecerf (2012)( 109 ) | |
| 27; 18–55 years | Mean (sem) | 35·8 (2·4) | 11·4 (1·2) | 10·0 (1·1) | 61·1 (4·4) | μmol/g | Reimer (2012)( 238 ) | |
| 12; 18–65 years | 48 | 13·98 | 13·31 | 80·91 | μmol/g | Fernando (2010)( 239 ) | ||
| 46; 31–66 years | Mean (95 % CI) | 44·7 (39·7, 50·3) females 58·6 (49·8, 69·0) males | 12·3 (10·7, 14·0) females 16·1 (13·4, 19·5) males | 11·7 (9·8, 14·0) females 15·4 (12·1, 19·6) males | 69·5 (61·3, 78·7) females 90·5 (76·3, 108) males | μmol/g | McOrist (2011)( 240 ) | |
| 36 | Median (IQR) | 43·7 (34·0–52·2) | 13·1 (9·2–18·5) | 8·8 (5·2–11·5) | 91·8 (73·1–107·5) | μmol/g | Nemoto (2012)( 241 ) | |
| 20; 22–55 years | Mean (sem) | 42·13 (3·84) | 11·5 (1·19) | 11·28 (1·42) | 67·3 (6·22) | μmol/g | Tiihonen (2010)( 67 ) | |
| 8; 31–59 years | Mean (sd) | NR | NR | NR | 92·7 (33·9) | μmol/g | McOrist (2008)( 242 ) | |
| 20; 23–28 years | Mean (sem) | NR | NR | NR | 78·5 (6·4) | μmol/g | Hylla (1998)( 243 ) | |
| 30 | Mean (sd) | 50·5 (12·6) | 13·6 (5·2) | 14·1 (7·6) | 84·6 (22·9) | mmol/l | Schwiertz (2010)( 64 ) | |
| Obese subjects | 20; 22–55 years | Mean (sem) | 47·15 (3·80) | 13·64 (1·34) | 14·73 (1·47) | 78·79 (6·19) | μmol/g | Tiihonen (2010)( 67 ) |
| 91 | Mean (sd) | 58·5 (19·1) | 17·6 (7·6) | 18·3 (9·7) | 102 (33·5) | mmol/l | Brinkworth (2009)( 63 ) | |
| 32; 20–65 years | Mean (sem) | NR | NR | NR | 34 (6) | mmol/24 h | Benassi Evans (2010)( 244 ) | |
| 35 overweight 33 obese | Mean (sd) | 56·0 (18·2) 59·8 (18·3) | 18·3 (7·9) 19·3 (8·7) | 18·5 (10·1) 18·1 (10·0) | 98·7 (33·9) 103·9 (34·3) | mmol/l | Schwiertz (2010)( 64 ) |
IQR, interquartile range; NR, not reported.