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. Author manuscript; available in PMC: 2016 Jul 15.
Published in final edited form as: Eur J Med Chem. 2015 May 27;100:197–209. doi: 10.1016/j.ejmech.2015.05.042

Scheme 4.

Scheme 4

Synthesis of compounds 35–37. Reagents and conditions: (a) 1-(2-Aminoethyl)-closo-1,7-carborane [35], 1-(3-aminopropyl)-closo-1,7-carborane [35], or 1-(4-aminobutyl)-closo-1,7-carborane [35], CH3CN, overnight, 60 °C; (b) TBAF, THF, rt, 2 h.