TABLE III. Precision and accuracy data of back calculated concentrations of calibration samples for isoniazid (INH) in plasmaa .
Analyte | Nominal concentration (ng/mL) | Observed concentration (ng/mL - mean ± SD) | Precision (RSD) (%) | Accuracy (%) |
---|---|---|---|---|
INH | 100 | 97.28 ± 3.32 | 3.41 | 97.28 |
200 | 208.10 ± 15.31 | 7.36 | 104.05 | |
500 | 503.12 ± 43.11 | 8.57 | 100.62 | |
1,000 | 1.071.81 ± 10.44 | 0.97 | 107.18 | |
2,000 | 1.967.41 ± 18.50 | 0.94 | 98.37 | |
5,000 | 4.994.55 ± 179.65 | 3.60 | 99.89 | |
7,500 | 6.934.19 ± 488.77 | 7.05 | 92.46 |
a: two replicates per batch; RSD: relative standard deviation; SD: standard deviation.