Fig. 5. : antimalarial activity of the hydroxyethylamine derivatives. The mice were treated daily with artesunate (ART) or derivatives (10 mg/kg/day; intraperitoneally). Drug activity was evaluated at day 4 after infection and is expressed as (A) parasitaemia levels or as (B) activity, according the following equation: activity = 100 - [(mean parasitaemia treated/mean parasitaemia control) x 100]. It was used at least six animals per group in two different experiments.
