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. 2015 Jul 14;351:h3529. doi: 10.1136/bmj.h3529

Table 4 Effectiveness of implantable cardioverter defibrillators (ICDs) in demographic subgroups in latency 180 day* and latency 365 day* analyses

Sample size (ICD/no ICD) % of eligible patients received ICD Event (ICD/no ICD) IR† (ICD/no ICD) Adjusted HR (95% CI)‡
Latency 180 day Latency 365 day
Outcome=death
Age (years):
 66-70 1322/2534 34 285/568 127/137 0.89 (0.70 to 1.13) 1.02 (0.77 to 1.36)
 71-75 1347/2950 31 301/755 136/168 1.11 (0.88 to 1.40) 1.33 (1.02 to 1.74)
 76-80 1394/3670 28 362/1068 172/216 0.92 (0.75 to 1.12) 0.82 (0.65 to 1.04)
 ≥81 1195/8699 12 359/2908 213/345 0.78§ (0.65 to 0.93) 0.78§ (0.63 to 0.96)
Sex:
 Men 3763/9321 29 945/2779 161/245 0.92 (0.81 to 1.04) 0.96 (0.82 to 1.11)
 Women 1495/8532 14 362/2520 152/237 0.90 (0.75 to 1.07) 0.90 (0.74 to 1.10)
Race:
 White 4392/15 068 23 1088/4402 156/241 0.90 (0.81 to 1.01) 0.96 (0.84 to 1.10)
 Black 613/1790 26 154/594 172/240 0.93 (0.70 to 1.24) 0.82 (0.57 to 1.16)
 Other 253/995 20 65/303 181/240 0.94 (0.60 to 1.47) 0.84 (0.50 to 1.39)
Outcome=sudden cardiac death
Age (years):
 66-70 1322/2534 34 73/125 33/30 1.04 (0.63 to 1.72) 1.12 (0.62 to 2.00)
 71-75 1347/2950 31 59/176 27/39 0.81 (0.48 to 1.35) 0.73 (0.41 to 1.27)
 76-80 1394/3670 28 99/215 47/44 1.43 (0.95 to 2.14) 1.30 (0.82 to 2.07)
 ≥81 1195/8699 12 99/810 59/96 0.74 (0.52 to 1.04) 0.80 (0.54 to 1.18)
Sex:
 Men 3763/9321 29 248/732 42/65 1.00 (0.78 to 1.28) 1.08 (0.82 to 1.42)
 Women 1495/8532 14 82/594 35/56 0.86 (0.59 to 1.26) 0.75 (0.50 to 1.15)
Race:
 White 4392/15 068 23 288/1121 41/61 0.98 (0.79 to 1.23) 1.06 (0.82 to 1.36)
 Black 613/1790 26 31/135 35/54 0.77 (0.40 to 1.47) 0.44 (0.20 to 1.00)
 Other 253/995 20 11/70 31/55 0.75 (0.24 to 2.33) 0.60 (0.16 to 2.22)

*Latency 180 day analyses: starting follow-up from 180 days after index time; latency 365 day analyses: starting follow-up from 365 days after index time

†IR=incidence rate per 1000 person years.

‡Adjusted for high dimension propensity score.

§P<0.05.