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. 2015 Jul 14;351:h3529. doi: 10.1136/bmj.h3529

Table 5 Effectiveness of implantable cardioverter defibrillators (ICDs) in clinical subgroups in latency 180 day* and latency 365 day* analyses

Sample size (ICD/no ICD) % of eligible patients received ICD Event (ICD/no ICD) IR† (ICD/no ICD) Adjusted HR (95% CI)‡
Latency 180 day Latency 365 day
Outcome=death
Myocardial infarction:
 Recent 1685/8160 17 565/4476 165/333 0.92 (0.77 to 1.09) 0.94 (0.76 to 1.16)
 Old 448/904 33 186/648 226/532 0.63§ (0.45 to 0.86) 0.74 (0.51 to 1.08)
 No 3125/8789 26 1108/5317 172/369 0.90 (0.79 to 1.03) 0.91 (0.78 to 1.07)
Left bundle branch block:
 No 5143/17 406 23 1809/10 161 173/358 0.92 (0.83 to 1.01) 0.94 (0.83 to 1.06)
 Yes 115/447 20 50/280 213/401 0.64 (0.34 to 1.17) 0.75 (0.37 to 1.49)
B type natriuretic peptide:
 <800 1085/1604 40 359/905 157/302 0.86 (0.67 to 1.10) 0.86 (0.65 to 1.15)
 ≥800 1006/3439 23 490/2373 278/464 0.94 (0.78 to 1.13) 0.91 (0.72 to 1.13)
Outcome=sudden cardiac death
Myocardial infarction:
 Recent 1685/8160 17 115/542 34/40 1.03 (0.76 to 1.39) 0.92 (0.64 to 1.33)
 Old 448/904 33 27/83 33/68 0.74 (0.40 to 1.35) 1.12 (0.56 to 2.21)
 No 3125/8789 26 188/701 29/49 0.91 (0.70 to 1.18) 1.00 (0.73 to 1.38)
Left bundle branch block:
 No 5143/17 406 23 325/1289 31/45 0.97 (0.80 to 1.17) 1.02 (0.81 to 1.29)
 Yes 115/447 20 5/37 21/53 0.51 (0.16 to 1.61) 0.42 (0.09 to 2.05)
B type natriuretic peptide:
 <800 1085/1604 40 92/199 40/66 1.11 (0.69 to 1.77) 1.42 (0.82 to 2.46)
 ≥800 1006/3439 23 132/539 75/105 1.20 (0.85 to 1.69) 1.17 (0.76 to 1.80)

*Latency 180 day analyses: starting follow-up from 180 days after index time; latency 365 day analyses: starting follow-up from 365 days after index time.

†IR=incidence rate per 1000 person years.

‡Adjusted for high dimension propensity score.

§P<0.05.