Table 5 Effectiveness of implantable cardioverter defibrillators (ICDs) in clinical subgroups in latency 180 day* and latency 365 day* analyses
| Sample size (ICD/no ICD) | % of eligible patients received ICD | Event (ICD/no ICD) | IR† (ICD/no ICD) | Adjusted HR (95% CI)‡ | ||
|---|---|---|---|---|---|---|
| Latency 180 day | Latency 365 day | |||||
| Outcome=death | ||||||
| Myocardial infarction: | ||||||
| Recent | 1685/8160 | 17 | 565/4476 | 165/333 | 0.92 (0.77 to 1.09) | 0.94 (0.76 to 1.16) |
| Old | 448/904 | 33 | 186/648 | 226/532 | 0.63§ (0.45 to 0.86) | 0.74 (0.51 to 1.08) |
| No | 3125/8789 | 26 | 1108/5317 | 172/369 | 0.90 (0.79 to 1.03) | 0.91 (0.78 to 1.07) |
| Left bundle branch block: | ||||||
| No | 5143/17 406 | 23 | 1809/10 161 | 173/358 | 0.92 (0.83 to 1.01) | 0.94 (0.83 to 1.06) |
| Yes | 115/447 | 20 | 50/280 | 213/401 | 0.64 (0.34 to 1.17) | 0.75 (0.37 to 1.49) |
| B type natriuretic peptide: | ||||||
| <800 | 1085/1604 | 40 | 359/905 | 157/302 | 0.86 (0.67 to 1.10) | 0.86 (0.65 to 1.15) |
| ≥800 | 1006/3439 | 23 | 490/2373 | 278/464 | 0.94 (0.78 to 1.13) | 0.91 (0.72 to 1.13) |
| Outcome=sudden cardiac death | ||||||
| Myocardial infarction: | ||||||
| Recent | 1685/8160 | 17 | 115/542 | 34/40 | 1.03 (0.76 to 1.39) | 0.92 (0.64 to 1.33) |
| Old | 448/904 | 33 | 27/83 | 33/68 | 0.74 (0.40 to 1.35) | 1.12 (0.56 to 2.21) |
| No | 3125/8789 | 26 | 188/701 | 29/49 | 0.91 (0.70 to 1.18) | 1.00 (0.73 to 1.38) |
| Left bundle branch block: | ||||||
| No | 5143/17 406 | 23 | 325/1289 | 31/45 | 0.97 (0.80 to 1.17) | 1.02 (0.81 to 1.29) |
| Yes | 115/447 | 20 | 5/37 | 21/53 | 0.51 (0.16 to 1.61) | 0.42 (0.09 to 2.05) |
| B type natriuretic peptide: | ||||||
| <800 | 1085/1604 | 40 | 92/199 | 40/66 | 1.11 (0.69 to 1.77) | 1.42 (0.82 to 2.46) |
| ≥800 | 1006/3439 | 23 | 132/539 | 75/105 | 1.20 (0.85 to 1.69) | 1.17 (0.76 to 1.80) |
*Latency 180 day analyses: starting follow-up from 180 days after index time; latency 365 day analyses: starting follow-up from 365 days after index time.
†IR=incidence rate per 1000 person years.
‡Adjusted for high dimension propensity score.
§P<0.05.