Scheme 2.
Synthesis of extended 2,7-bisacetylamidofluorenone analogs. Reaction conditions and reagents: (a) bromoacetyl bromide, xylene, reflux, 40%; (b) benzyloxyacetyl chloride, xylene, reflux, 26% for 15; (c) maleic anhydride, CHCl3, 26% for 16; (d) NaOH, EtOH, 86% for 12; (e) methoxyethanol, NaH, CH3CN, 18% for 13; (f) NaN3, DMF, 24% for 14.