MPO activity in colonic tissue of water-treated control mice, animals receiving DSS, DSS + PBS, DSS + rhA-IV (0.5 mg or 0.25 mg), DSS + BSA, or DSS + rhA-I, after 7 days. Tissue MPO was measured as described in Methods (mean ± SE). †P < 0.05 vs. water, *P < 0.05 vs. DSS, #P < 0.05 vs. DSS + PBS, P < 0.05 vs. DSS + BSA, sP < 0.05 vs. DSS + rhA-I.