Figure 2.

TIPE2 increases Bcl-2 protein expression and blocks Fas and FasL protein expression in thymus T cells from septic mice. Groups of mice were induced by caecal ligation and puncture for 24 h. Results were obtained by densitometric analysis of western blots of Bcl-2, Fas and FasL protein. Values are expressed as the mean ± standard deviation of three independent experiments. Non-septic group: ^*P<0.05 vs. wild-type mice; septic group: ^#P<0.05 vs. wild-type mice. TIPE2, tumor necrosis factor-α-inducible protein 8-like 2; Bcl-2, B-cell lymphoma 2; FasL, Fas ligand.