Figure 6.

Rhodiola rosea extract inhibits the expression of TIPE2, Fas and FasL mRNA in the thymus of septic mice. Groups of mice were treated with Rhodiola rosea extract and 8 h later challenged by caecal ligation and puncture for 24 h. Expression of TIPE2, Bcl-2, Fas and FasL mRNA was determined using reverse transcription polymerase chain reaction and quantified by densitometric analysis. Values are expressed as the mean ± standard error of the mean. ^*P<0.05, ^**P<0.01 vs. sham operation group and normal control group; ^#P<0.05 vs. control group. TIPE2, tumor necrosis factor-α-inducible protein 8-like 2; Bcl-2, B-cell lymphoma 2; FasL, Fas ligand.