Table 2. Summary of ERG, SPINK1, and ERG/SPINK1 by pathological features.
| Feature | Status | ERG Neg | ERG Pos | P-value | SPINK1 Neg | SPINK1 Pos | P-value | Both Neg | Either Pos | P-value |
|---|---|---|---|---|---|---|---|---|---|---|
| Surgical Margin | Positive | 168(61.5%) | 105(38.5%) | 0.08 | 264(96%) | 11(4%) | 1.00 | 158(57.9%) | 115(42.1%) | 0.13 |
| Negative | 285(55%) | 233(45%) | 505(96.2%) | 20(3.8%) | 270(52.1%) | 248(47.9%) | ||||
| Stage | III/IV | 142(61.5%) | 89(38.5%) | 0.26 | 227(97.4%) | 6(2.6%) | 0.31 | 137(59.3%) | 94(40.7%) | 0.13 |
| I/II | 302(56.9%) | 229(43.1%) | 514(95.5%) | 24(4.5%) | 282(53.1%) | 249(46.9%) | ||||
| SVinv | Negative | 482(54.9%) | 396(45.1%) | 0.09 | 856(96.6%) | 30(3.4%) | 1.00 | 458(52.2%) | 420(47.8%) | 0.11 |
| Yes | 41(66.1%) | 21(33.9%) | 61(96.8%) | 2(3.2%) | 39(62.9%) | 23(37.1%) | ||||
| ECE | Negative | 385(54.8%) | 318(45.2%) | 0.18 | 682(95.9%) | 29(4.1%) | 0.10 | 361(51.4%) | 342(48.6%) | 0.05 |
| Yes | 146(59.8%) | 98(40.2%) | 241(98.4%) | 4(1.6%) | 143(58.6%) | 101(41.4%) | ||||
| Gleason Score | < = 6 | 190(51.8%) | 177(48.2%) | 0.01 | 362(97.1%) | 11(2.9%) | 0.63 | 183(49.9%) | 184(50.1%) | 0.03 |
| 3+4 | 198(55%) | 162(45%) | 347(96.1%) | 14(3.9%) | 186(51.7%) | 174(48.3%) | ||||
| 4+3 | 83(66.4%) | 42(33.6%) | 122(97.6%) | 3(2.4%) | 80(64%) | 45(36%) | ||||
| 8–10 | 61(64.2%) | 34(35.8%) | 92(94.8%) | 5(5.2%) | 56(58.9%) | 39(41.1%) |
P-values by Fisher’s exact test.