Table 2. Expected and identified frequency of patients with IDO2 Variant Alleles.
| Recessive Logistic Model | Number (and %) of minor alleles | |||||
|---|---|---|---|---|---|---|
| Predicted Minor allele frequency | Estimate coefficient | P-value | Race | Non-IBD (N = 177) | CD (N = 686) | |
| rs4503083 (T to A) | 10.9%–50.0% | -1.295 | 0.025 | White | het: 58 (40.8%) | het: 196 (31.9%) |
| Y359stop | homo: 8 (5.6%) | homo: 19 (3.1%) | ||||
| total: 142 | total: 614 | |||||
| Black | het: 5 (14.7%) | het: 12 (19%) | ||||
| homo: 1 (2.9%) | homo: 1 (1.6%) | |||||
| total: 34 | total: 63 | |||||
| Other | het: 0 (0%) | het: 7 (77.8%) | ||||
| homo: 0 (0%) | homo: 0 (0%) | |||||
| total: 1 | total: 9 | |||||
| rs4736794 (A to G) | 6.7%–50.0% | -0.498 | 0.698 | White | het: 27 (19%) | het: 92 (15%) |
| homo: 2 (1.4%) | homo: 4 (0.7%) | |||||
| total: 142 | total: 614 | |||||
| Black | het: 2 (5.9%) | het: 2 (3.2%) | ||||
| homo: 0 (0%) | homo: 0 (0%) | |||||
| total: 34 | total:63 | |||||
| Other | het: 0 (0%) | het: 6 (66.7%) | ||||
| homo: 0 (0%) | homo: 0(0%) | |||||
| total: 1 | total: 9 | |||||
| rs10109853 (C to T) | 18.2%–100% | -0.072 | 0.786 | White | het: 65 (45.8%) | het: 316 (51.5%) |
| homo: 32 (22.5%) | homo: 157 (25.6%) | |||||
| total: 142 | total: 614 | |||||
| Black | het: 13 (38.2%) | het: 26 (41.3%) | ||||
| homo: 7 (20.6%) | homo: 9 (14.3%) | |||||
| total: 34 | total: 63 | |||||
| Other | het: 0 (0%) | het: 6 (66.7%) | ||||
| homo: 1 (100%) | homo: 1 (11.1%) | |||||
| total: 1 | total: 9 | |||||
| rs35212142(T to A) | 5.6%–50.0% | 12.923 | 0.981 | White | het: 8 (5.6%) | het: 26 (4.2%) |
| homo: 0 (0%) | homo: 2 (0.3%) | |||||
| total: 142 | total: 614 | |||||
| Black | het: 2 (5.9%) | het: 0 (0%) | ||||
| homo: 0 (0%) | homo: 0 (0%) | |||||
| total: 34 | total: 63 | |||||
| Other | het: 0 (0%) | het: 0 (0%) | ||||
| homo: 0 (0%) | homo: 0 (0%) | |||||
| total: 1 | total: 9 | |||||