Table 2.

Univariate logistic regression for IDO scores—low versus medium/high

Variable	Reference	Level	OR (95 % CI)	p value(1)	p value(2)
Race	African American	European American	1.4 (0.79–2.46)	0.2457	0.2457
Age			1 (1–1.01)	0.5543
BMI	24.9 or <	25–29.9	1.61 (0.76–3.42)	0.2140	0.4615
	24.9 or <	30 or >	1.26 (0.63–2.53)	0.5122
Age			1 (0.98–1.02)	0.8812
Metastasis	Negative	Positive	2.37 (0.21–26.56)	0.4847	0.4847
Tumor size	TIS/1/2	3/4	0.45 (0.22–0.92)	0.0282	0.0282
Node	0	1+	0.51 (0.28–0.93)	0.0281	0.0281
Tumor grade	1	2	0.9 (0.37–2.21)	0.8189	0.2003
	1	3	0.54 (0.23–1.29)	0.1684
Estrogen receptor	Negative	Positive	2.25 (1.26–4.04)	0.0064	0.0064
Progesterone receptor	Negative	Positive	1.36 (0.75–2.45)	0.3119	0.3119
HER2–neu receptor	Negative	Positive	1.09 (0.52–2.29)	0.8262	0.8262
p53 mutation status	Negative	Positive	0.73 (0.36–1.51)	0.4000	0.4000
EGFR	1	2	0.79 (0.11–5.66)	0.8180	0.0013
	1	3	0.96 (0.13–6.95)	0.9712
	1	4	9.64 (1.63–56.92)	0.0124
EGFR	1/2	3/4	4.46 (1.42–14.01)	0.0106	0.0106
CK 5/6	1/2	3/4	0.54 (0.15–1.88)	0.3333	0.3333
CD31	≤39.5	>39.5	0.43 (0.24–0.77)	0.0041	0.0041
pAKT473	1/2	3/4	1.87 (0.87–4)	0.1063	0.1063
p-caspase 9	1/2/3	4	1.89 (1.08–3.31)	0.0263	0.0263
NOS2	1/2/3	4	2.22 (1.26–3.92)	0.0057	0.0057
COX2	1/2	3/4	2.14 (1.2–3.83)	0.0100	0.0100

(1) Specific-level p value, (2) overall variable p value

Bold values indicate statistical significance p < 0.05