Table 2.

Blood-oxygen-level-dependent response to emotional dynamics. Clusters shown are those containing voxel-wise maxima with P_corr<0.05 after small volume correction using bilateral automated anatomical labelling masks. Coordinates are quoted using the Montreal Neurological Institute spatial reference

Drug condition	Region	x	y	z	Zpeak	Voxel-wise Pcorr	Cluster (mm3)
Emotional exposure: negative­–arousing vs neutral
Placebo	Negative–arousing > neutral
	Right amygdala	24	0	−15	4.14	0.002	513
	Left amygdala	−18	0	−15	3.43	0.020	108
	Left hippocampus	−12	−36	0	4.86	0.001	486
	Right hippocampus	21	−33	−3	3.88	0.018	351
Propofol	Negative–arousing > neutral
	Right amygdala	27	−3	−12	4.41	0.001	972
	Left amygdala	−24	0	−15	3.80	0.008	297
Propofol vs Placebo	Propofol < placebo
	Right hippocampal–parahippocampal junction	18	−36	−6	−3.59	0.038	108