Table 1.
Characteristics of TN and psychiatric illness and comparison subjects
| TN and psychiatric illness | Control cohort | P values | ||
|---|---|---|---|---|
| No. | 3273 | 13,092 | ||
| Age (years)a | 45.6 (33.9–54.8) | 45.6 (33.9–54.8) | 0.999 | |
| Distribution of age | ||||
| 20–39 | 1299 (39.7) | 5196 (39.7) | 0.999 | |
| 40–59 | 1423 (43.5) | 5692 (43.5) | 0.999 | |
| ≥60 | 551 (16.8) | 2204 (16.8) | 0.999 | |
| Sex | ||||
| Female | 1255 (38.3) | 5020 (38.3) | 0.999 | |
| Male | 2018 (61.7) | 8072 (61.7) | ||
| Comorbidities | ||||
| Hypertension | 725 (22.2) | 2192 (16.7) | <0.001* | |
| Diabetes mellitus | 442 (13.5) | 1285 (9.8) | <0.001* | |
| Dyslipidemia | 717 (21.9) | 1795 (13.7) | <0.001* | |
| Coronary artery disease | 25 (0.8) | 91 (0.7) | 0.650 | |
| Congestive heart failure | 71 (2.2) | 226 (1.7) | 0.090 | |
| Cerebrovascular disease | 134 (4.1) | 421 (3.2) | 0.014 | |
| Chronic pulmonary disease | 591 (18.1) | 1318 (10.1) | <0.001* | |
| Malignancy | 48 (1.5) | 213 (1.6) | 0.581 | |
| Income | <0.001* | |||
| Low income | 1199 (36.6) | 5732 (43.8) | ||
| Medium income | 1315 (40.2) | 4982 (38.1) | ||
| High income | 759 (23.2) | 2378 (18.2) | ||
| Degree of urbanization | 0.072 | |||
| Urban | 2112 (64.5) | 8172 (62.4) | ||
| Suburban | 938 (28.7) | 3940 (30.1) | ||
| Rural | 223 (6.8) | 980 (7.5) | ||
| Follow-up, yearsa | 3.08 (1.92–3.98) | 3.08 (1.92–3.99) | 0.852 | |
| Newly diagnosed psychiatric disorders, N (%) | ||||
| Schizophrenia | 3 (0.09) | 5 (0.04) | 1.000 | |
| Bipolar disorder | 1 (0.09) | 6 (0.05) | 0.203 | |
| Depressive disorder | 73 (2.23) | 103 (0.79) | <0.001* | |
| Anxiety disorder | 59 (1.80) | 79 (0.60) | <0.001* | |
| Sleep disorder | 40 (1.22) | 74 (0.57) | <0.001* | |
aMedian (interquartile range)
*Statistical significance