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Characteristics of groups of Type 1 diabetic patients analysed for HLA associations with HLA gene expression and for T-cell responses
| HLA-Ab associations | T-cell analysis | |
|---|---|---|
|
| ||
| Number | 127 | 58 |
| Age at diagnosis (mean years ± SD) | 17 ± 5.6 | 18 ± 5.1 |
| Sex (% male) | 68.5 | 74.1 |
| Autoantibodies | ||
| IA-2A (% positive) | 68.5 | 55.2 |
| GADA (% positive) | 79.5 | 82.7 |
| ZnT8A (% positive) | 59.0 | 55.2 |
| HLA | ||
| DR3/4 (%) | 27.6 | 30.9 |
| DR4/x (%) | 33.9 | 34.5 |
| DR3/x (%) | 26.0 | 23.6 |
| non-DR3/4 (%) | 12.6 | 10.9 |
