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. 2015 Jul 15;35(28):10154–10167. doi: 10.1523/JNEUROSCI.3708-14.2015

Figure 4.

Figure 4.

Genetic interaction tests with dDAAM and the PCP genes. A, Quantification of the MB axonal growth and guidance defects in mutant combinations of dDAAMEx1and the core PCP mutants fmi, pk, Vang, and fz. dDAAM shows a dominant genetic interaction with fmifrz3, pk30, Vangstbm-6, but the fz30 allele. B, Quantification of the MB axonal growth and guidance defects in dDAAMEx1 and fz20 single or double homozygous mutants. The dDAAMEx1; fz20 double mutant displays a synergistic enhancer effect in both lobes. C, Quantification of the MB axonal growth and guidance defects in dDAAMEx1and dsh1 mutant combinations. Double mutants hardly develop normal looking lobes, and dsh1 displays a strong dominant interaction with dDAAM. ***p ≤ 0.0001 (Fisher's exact test). **0.0001< p < 0.005 (Fisher's exact test). *0.005< p < 0.05 (Fisher's exact test).