Figure 2.

AIB signaling modulates both spontaneous and sensory-evoked reversal behavior differentially. A, B, Aversive responses to dilute 1-octanol without and with 4 mm 5-HT (black and white bars, respectively) and spontaneous reversals were examined in wild-type and transgenic animals. egl-1, TeTx, mod-1, and glr-1 cDNAs were expressed in the AIBs under the npr-9 or inx-1 promoters in wild-type backgrounds. npr-9, inx-1, and odr-2(2b) promoters are labeled as 1, 2, and 3, respectively. eat-4- and mod-1-selective RNAi was performed using the npr-9 promoter. Data represent mean ± SEM with 15–20 animals being tested in 3 independent experiments and were analyzed by two-tailed Student's t test with Welch's correction. *p < 0.001, significantly different from wild-type animals under identical conditions.