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. 2015 Jun 12;35(5):491–500. doi: 10.1007/s10875-015-0172-2

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© The Author(s) 2015

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 6 — Representative MRI sequences in a patient at diagnosis and after 12 months In a 18 years old man who started Ig replacement therapy (patient n. 4), MRI BLADE sequence at first MRI showed multiple distal mucus plugs with branching patterns (“tree in bud” appearance) of the left upper lobe (white arrows) (a); these abnormalities regressed at the second MRI assessment after 12 months (white arrows) (b). MRI BLADE sequence at first MRI showed one nodule (white arrow) at the right lower lobe (c); the nodule showed a reduction in size at the second MRI assessment after 12 months (white arrow) (d)