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Half-maximal inhibitory concentrations (IC50) estimated for RVT and 3,3′,4,4′-THS according to the results of MTT and LDH release assays.
| MTT assay | LDH release assay | |||
|---|---|---|---|---|
| RVT | 3,3′,4,4′-THS | RVT | 3,3′,4,4′-THS | |
| A2780 | 48 μM | 4 μM | 65 μM | 6 μM |
| OVCAR-3 | 480 μM | 50 μM | 525 μM | 85 μM |
| SKOV-3 | 380 μM | 8 μM | 346 μM | 10 μM |
| HOSE cells | 485 μM | 502 μM | 421 μM | 532 μM |
| HPMCs | 465 μM | 496 μM | 495 μM | 498 μM |
