Table 4.
Univariate Cox proportional hazard analysis for the association of biomarkers with the occurrence of hypertension in lone AF patients.
| Biomarkers | Unadjusted Cox analysis | Biomarker predictive ability (per quartile increase) | Pairwise comparison of biomarker predictive ability (per quartile increase) | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | c-statistic | 95% CI | P value | z-statistic | 95% CI | P value | |
| CRP (quartiles)∗ | 2.35 | (1.25–4.39) | 0.008 | 0.763 | 0.627–0.899 | 0.004 | 1.62 (CRP versus oxLDL) |
−0.02–0.23 | 0.1005 |
| oxLDL (quartiles)∗ | 2.55 | (1.33–4.89) | 0.005 | 0.879 | 0.787–0.971 | <0.001 | |||
HR: hazard ratio; CI: confidence interval.
∗1st, 2nd, 3rd, and 4th quartiles of biomarkers, respectively: CRP: <0.80 mg/L; 0.80 to <1.58 mg/L; 1.58 to <2.70 mg/L; ≥2.70 mg/L; oxLDL: <49.5 U/L; 49.5 to <61.5 U/L; 61.5 to <79.0 U/L; ≥79.0 U/L.