Table 3.
Responsiveness to change of the Saint George’s Respiratory Questionnaire at 1 year compared with physician and patient disease assessments
| Overall score change | Improved, physiciana | Unimproved, physician1 | Improved, patient1 | Unimproved, patient1 | |
|---|---|---|---|---|---|
| SYM | |||||
| Mean (s.d.) | −0.88 (19.38) | −5.27 (19.61) | 4.53 (17.98) | −3.34 (17.22) | 2.30 (22.07) |
| n | 98 | 53 | 37 | 54 | 42 |
| Effect size | −0.04 | −0.27 | 0.22 | −0.18 | 0.11 |
| P-value | — | 0.02 | — | 0.17 | — |
| ACT | |||||
| Mean (s.d.) | −0.77 (24.36) | −7.95 (23.51) | 7.95 (22.48) | −5.17 (23.37) | 3.95 (25.03) |
| n | 92 | 49 | 35 | 50 | 40 |
| Effect size | −0.02 | −0.25 | 0.23 | −0.16 | 0.11 |
| P-value | — | 0.002 | — | 0.08 | — |
| IMPACT | |||||
| Mean (s.d.) | −1.20 (15.65) | −3.58 (14.74) | 0.56 (15.48) | −4.03 (11.91) | 2.19 (22.07) |
| n | 90 | 48 | 36 | 49 | 40 |
| Effect size | −0.07 | −0.21 | 0.03 | −0.21 | 0.14 |
| P-value | — | 0.22 | — | 0.08 | — |
| TOTAL | |||||
| Mean (s.d.) | −1.09 (16.52) | −5.35 (15.51) | 3.56 (16.25) | −4.83 (12.79) | 3.13 (19.53) |
| n | 85 | 45 | 34 | 46 | 38 |
| Effect size | −0.05 | −0.26 | 0.17 | −0.23 | 0.15 |
| P-value | — | 0.02 | — | 0.03 | — |
aAt 1 year, physicians and patients rated the change in the patient’s overall scleroderma severity on a scale of 1 (much better) to 5 (much worse). Scores of 1 and 2 were considered improved, scores 3–5 were considered unimproved. P-values for the reported group compared with the corresponding unimproved group. ACT: activity scale; IMPACT: impact scale; TOTAL: total score.