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. 2015 Jul 15;9:184. doi: 10.3389/fnbeh.2015.00184

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Copyright © 2015 Bravo-Rivera, Roman-Ortiz, Montesinos-Cartagena and Quirk.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution and reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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c-Fos expression at post-extinction avoidance test. (A) Schematic showing experimental protocol. (B) Representative micrographs of c-Fos immuno-labeling. (C) Task 1 revealed positive correlations between avoidance expression at test and c-Fos density in PL, ventral striatum (VS), basal amygdala (BA), and OFC, and a negative correlation in IL (correlation value in inset). (D) Task 2 revealed positive correlations in PL, VS and OFC only. (E) Comparison of c-Fos density in BA and IL in Task 1. (F) Comparison of c-Fos density in BA and IL in Task 2. Darker hues represent higher avoidance whereas lighter hues represent lower avoidance. ***p < 0.001 and **p < 0.01.