Table 5. List of KEGG pathways for which at least two enzymes are differentially expressed at 25°.
| KEGG Pathways Upregulated at 25° | KEGG Pathways Downregulated at 25° | ||
|---|---|---|---|
| Pathway | # Enzymes | Pathway | # Enzymes |
| Purine metabolism | 7 | Purine metabolism | 22 |
| One carbon pool by folate | 6 | Phosphatidylinositol signaling system | 11 |
| Arginine and proline metabolism | 5 | Glycerophospholipid metabolism | 10 |
| Amino sugar and nucleotide sugar metabolism | 5 | Amino sugar and nucleotide sugar metabolism | 9 |
| Glycine, serine, and threonine metabolism | 4 | Inositol phosphate metabolism | 9 |
| Pyrimidine metabolism | 4 | Pyrimidine metabolism | 8 |
| Arachadonic acid metabolism | 4 | Pyruvate metabolism | 8 |
| Cysteine and methionine metabolism | 4 | Citrate cycle | 7 |
| Mucin type O-glycan biosynthesis | 4 | Pentose and glucuronate interconversions | 7 |
| Fructose and mannose metabolism | 4 | Fructose and mannose metabolism | 7 |
| Lysine degradation | 3 | Glycine, serine, and threonine metabolism | 7 |
| Aminoacyl-tRNA biosynthesis | 3 | Glutathione metabolism | 7 |
| Sphingolipid metabolism | 3 | Glycerolipid metabolism | 7 |
| Terpenoid backbone biosynthesis | 3 | Carbone fixation pathways in prokaryotes | 7 |
| Other types of O-glycan biosynthesis | 3 | Alanine, aspartate, and glutamate metabolism | 6 |
| Starch and sucrose metabolism | 3 | Tryptophan metabolism | 6 |
| Carbon fixation pathways in prokaryotes | 3 | Arachadonic acid metabolism | 6 |
| T-cell receptor signaling pathway | 2 | Porphyria and chlorophyll metabolism | 6 |
| Porphyrin and chlorophyll metabolism | 2 | Glycolysis/gluconeogenesis | 5 |
| Steroid biosynthesis | 2 | Pentose phosphate pathway | 5 |
| Glycosphingolipid biosynthesis—lacto and neglector series | 2 | Arginine and proline metabolism | 5 |
| Drug metabolism—other enzymes | 2 | Glycosylate and dicarboxylate metabolism | 5 |
| Alanine, aspartate and glutamate metabolism | 2 | Butanoate metabolism | 5 |
| Folate biosynthesis | 2 | Aminoacyl-tRNA biosynthesis | 5 |
| Linoleic acid metabolism | 2 | Galactose metabolism | 4 |
| Fatty acid degradation | 4 | ||
| Valine, leucine, and isoleucine degradation | 4 | ||
| Lysine degradation | 4 | ||
| Starch and sucrose metabolism | 4 | ||
| Glycosaminoglycan degradation | 4 | ||
| Ether lipid metabolism | 4 | ||
| Sphingolipid metabolism | 4 | ||
| Methane metabolism | 4 | ||
| Drug metabolism | 4 | ||
| Ascorbate and alderate metabolism | 3 | ||
| Synthesis and degradation of ketone bodies | 3 | ||
| Steroid hormone biosynthesis | 3 | ||
| Cysteine and methionine metabolism | 3 | ||
| Beta-alanine metabolism | 3 | ||
| Various types of N-glycan biosynthesis | 3 | ||
| Alpha-linolenic acid metabolism | 3 | ||
| Glycosphingolipid biosynthesis-globoseries | 3 | ||
| Propanoate metabolism | 3 | ||
| One carbon pool by foliate | 3 | ||
| Retinol metabolism in animals | 3 | ||
| Metabolism by xenobiotics by cytochrome P450 | 3 | ||
| Drug metabolism—cytochrome P450 | 3 | ||
| Geraniol degradation | 2 | ||
| Histidine metabolism | 2 | ||
| Tyrosine metabolism | 2 | ||
| Phenylalanine metabolism | 2 | ||
| Cyanoamino acid metabolism | 2 | ||
| N-glycan biosynthesis | 2 | ||
| Peptidoglycan biosynthesis | 2 | ||
| Linoleic acid metabolism | 2 | ||
| Chloroalkane and chloroalkene degradation | 2 | ||
| Aminobenzoate degradation | 2 | ||
| Carbone fixation in photosynthetic organisms | 2 | ||
| Nicotinate and nicotinamide metabolism | 2 | ||
| Nitrogen metabolism | 2 | ||
| Phenylpropanoid biosynthesis | 2 | ||
| mTOR signaling pathway | 2 | ||
| T-cell receptor signaling pathway | 2 |
Several KEGG pathways are represented in both the upregulated and downregulated groups. For these common pathways, different enzymes are upregulated or downregulated.