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Mutational synergy of SNP1-(1-223) and SNP1-(1-208) with CBC2-Y24A. The wild-type and truncated SNP1 alleles were tested for activity by plasmid shuffle in CBC2 snp1∆ and CBC2-Y24A snp1∆ strains. FOA-resistant isolates were spot-tested for growth on YPD agar at the temperatures specified. Synthetic growth defects are denoted by •.
