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. Author manuscript; available in PMC: 2015 Jul 15.
Published in final edited form as: Neuroimage. 2010 Feb 13;53(3):810–821. doi: 10.1016/j.neuroimage.2010.02.019

Fig. 1.

Fig. 1

Summary of the genetic impact of mood disorder risk genes on volumetric and BOLD measures in healthy subjects and mood disorder patients. BOLD, blood-oxygen level dependent. ○, only studies in mood disorder samples available; ●, only studies in healthy samples available; +, only gene–gene interaction reported; *, gene–environment interaction reported; three classes of color opacity display available evidence (from light to dark): 30% single study or support index <0.5; 60% support index 0.5–0.75; 100% support index N0.75; further details on the calculation of the support index can be found in Supplementary data; ACC, anterior cingulate cortex; OFC, orbitofrontal cortex; AMY–ACC, amygdala–anterior cingulate cortex circuitry; AMY, amygdala; HIPP, hippocampus. Gene nomenclature corresponds to OMIM (Online Mendelian Inheritance in Man).