Figure 2. X-ray crystal structures of human molecules involved in immunology and allergic disease.
A) Complex of a human α/β-T cell receptor (orange and yellow), influenza HA antigen peptide (blue), and MHC Class II molecule, HLA-DR1 (green and fuchsia) (1FYT); B) cytokine receptor IL4 Type I (blue and green) bound to cytokine IL-4 (fuchsia) (3BPL); C) IgE-Fc (Cε2, Cε3 and Cε4 domains) (blue and fuchsia) bound to the extracellular domains of the high affinity IgE receptor (FcεRI) α chain (yellow) (2Y7Q); D) low affinity IgE receptors (CD23, FcεRII) (4G9A); and E) Toll-like receptor 4 (blue and fuchsia)-MD2 (yellow)-LPS (green) complex (3FXI).