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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: J Allergy Clin Immunol. 2015 Jul;136(1):29–37.e10. doi: 10.1016/j.jaci.2015.05.016

Figure 3. X-ray crystal structures of selected allergens.

Figure 3

A) Mus m 1 (1MUP); B) Bet v 1 (1BV1); C) Alt a 1 (3V0R); D) Bla g 1 (4JRB); E) Bla g 2 in complex with Fab of mAb 7C11 (2NR6; pink) superimposed with the mAb-Fab from the structure of Bla g 2 in complex with Fab of mAb 4C3 (3LIZ; green); F) Der p 1 in complex with 4C1 (pale yellow, 3RVW), superimposed with the mAb-Fab from the two structures of the allergen in complex with 10B9 (pale green; 4PP2) or 5H8 (pale orange, 4PP1); and G) Bos d 5 in complex with the Fab of a recombinant IgE antibody. Allergens are shown in rainbow colors from N (blue) to C-terminus (red), and ligands in magenta (A, D).