Figure 7.
The mitochondrial ultrastructure is undermined by TSPO. (A) Representative electron micrographs of the perinuclear region in MEFs in control (left panel) and +TSPO conditions (right panel). (B) Graph to show numbers of mitochondria in the perinuclear region in control and +TSPO MEFs, (n = 27 cells; P < 0.001). (C) Representative electron micrographs of individual mitochondria in MEFs in control (left panel) and +TSPO conditions (right panel). (D) Graph to show the average number of cristae per mitochondrion in control and +TSPO MEFs, (n = 18 cells; P < 0.001).