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. 2012 Oct 11;2(2):126–135. doi: 10.1093/jpids/pis091

Table 2.

Characteristics of HCV-Infected Infants and Their Mothers

Characteristic Case 1 Case 2 Case 3 Case 4 (Transient Infection)
Infant gestational age at birth (weeks) 39 38 33 40
Infant ALT value (U/L)

  • At hospital discharge after birth

  • At the 6–12-week visit

  • At the 6-month visit

 42
40
64		 16
52
402		 31
153
72		 12
12
12
Infant AST value (U/L)

  • At hospital discharge afterbirth

  • At the 6–12 week visit

  • At the 6-month visit

 88
39
95		 78
54
341		 31
267
72		 46
38
35
Maternal plasma HCV concentration at delivery (copies/mL) 11 272 865 3 585 026 4 478 552 7 235 918
Maternal plasma HIV concentration at delivery (copies/mL) 25 58 25 25
Maternal CD4 count at delivery (cells/mm3) 700 682 518 357
Mode of delivery Vaginal SCS SCS Vaginal
Infant HCV viral load (copies/mL)

  • At the 6–12-week visit

  • At the 6-month visit

 ≥40 000
695 741		 22 434 914
14 504 549		 4 585 007
Missing		 <3200
Negativea
Infant HCV genotype 1a 1a 1a 1a
Maternal HCV genotype 1 1a 1a 1a

Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; HCV, hepatitis C virus; HIV, human immunodeficiency virus; PCR, polymerase chain reaction; SCS, scheduled cesarean section.

aInfant tested HCV RNA-negative by qualitative HCV PCR testing.