Table 4.
Summary of study dog disposition and reason for study discontinuation (n and %)
| Dogs | Total (n) | % |
|---|---|---|
| Treated | 21 | 100 |
| Treated for all 4 or 5 cycles | 5 | 24 |
| Discontinued (for reason below) | 16 | 76 |
| Death due to progressive disease | 8 | 50 |
| Euthanasia due to progressive disease | 4 | 25 |
| Death due to adverse eventa | 2 | 12.5 |
| Other reasonb | 2 | 12.5 |
a
Grade 5 diarrhea (3 and 6 days after first cycle), probably died due to hemodynamic failure or sepsis.
b
Protocol noncompliance, withdrawal of owner consent, or reason not recorded.