Fig. 3.

Circulating FLRG and GASP-1 concentrations by LC-MS/MS in younger and older women and men. Box plots (25–75 percentile) and whiskers (Tukey method) showing comparisons of a FLRG, b GASP-1, c FLRG relative to myostatin, and d GASP-1 relative to myostatin between younger women (YW), older women (OW) and sarcopenic older women (SOW). Comparisons of myostatin inhibitors and their ratios to myostatin between corresponding groups of men are also illustrated (e-h). *, **, and *** denote p < 0.05, 0.01, and 0.001, respectively, compared to the younger group except when denoted with a bracket