Fig. 5.

Scan for evidence of recent directional selection by analysis of the standardised integrated haplotype score |iHS| for individual SNPs in Kintampo (N = 45) and Navrongo (N = 40). Additional file 1: Table S3 gives the co-ordinates and genes in 13 chromosomal regions containing windows of contiguous extended haplotype homozygosity attributed to two or more SNPs within the top 0.1 % of the expected distribution (|iHS| values > 3.29), with at least 1 SNP having |iHS| > 5 in these regions for the combined Ghana population. Most of these chromosomal regions are similar in both populations, as shown schematically in Figure 6