Table 1.
Comparison of mortality rate among control group, paraquat group and rapamycin treatment group at 1, 3, 5, and 7 days after intraperitoneal injection
| Group | 1 d (n = 12) | Mortality rate | 3 d (n = 12) | Mortality rate | 5 d (n = 12) | Mortality rate | 7 d (n = 12) | Mortality rate |
|---|---|---|---|---|---|---|---|---|
| Control group | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| PQ group | 4 | 33.3% | 6 | 50.0% | 6 | 50.0% | 10 | 83.3% |
| RAPA treatment group | 2 | 16.7% | 4 | 33.3% | 3 | 25.0% | 6 | 50% |
| χ2 | 4.80 | 7.75 | 8.00 | 17.10 | ||||
| P | 0.09 | 0.02 | 0.02 | < 0.01 | ||||
Control group, Sprague-Dawley rats were intraperitoneally injected with 1.25 ml/kg saline solution; PQ group, Sprague-Dawley rats were intraperitoneally injected with 15 ml/kg 2% paraquat solution; RAPA treatment group, paraquat-poisoned Sprague-Dawley rats were immediately intraperitoneally injected with 1.25 ml/kg saline solution containing 4 mg/kg rapamycin; 1 d, 3 d, 5 d, 7 d, 1, 3, 5, and 7 days after intraperitoneal injection.