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. 2015 May 1;8(5):4627–4638.

Table 3.

Comparison of leukocyte count and neutrophils percentage in blood and bronchoalveolar lavage fluid among control group, paraquat group and rapamycin treatment group at 1, 3, 5, and 7 days after intraperitoneal injection ( x̅ ± s)

Group Time n Blood BALF

Leukocyte count (× 109/L) Neutrophils percentage (%) leukocyte count (× 109/L) Neutrophils percentage (%)
Control group 1d 12 2.91 ± 1.21 13.75 ± 5.52 0.18 ± 0.03 21.25 ± 2.35
3 d 12 2.52 ± 1.18 15.69 ± 5.22 0.18 ± 0.02 21.05 ± 2.46
5 d 12 2.74 ± 1.43 16.94 ± 5.84 0.17 ± 0.01 21.53 ± 2.41
7 d 12 2.15 ± 1.13 15.50 ± 6.15 0.17 ± 0.04 20.89 ± 2.46
PQ group 1 d 12 7.95 ± 2.59a 41.50 ± 10.20a 0.32 ± 0.04a 41.15 ± 9.68a
3 d 12 9.02 ± 4.00a 51.78 ± 8.58a 0.39 ± 0.12a 42.37 ± 10.25a
5 d 12 8.54 ± 3.10a 55.42 ± 9.83a 0.48 ± 0.05a 44.70 ± 9.69a
7 d 12 8.57 ± 2.97a 57.67±9.68a 0.40 ± 0.05a 40.98 ± 4.76a
RAPA treatment group 1 d 12 6.46 ± 2.58a 40.62 ± 7.28a 0.32 ± 0.06a 40.45 ± 6.44a
3 d 12 6.10 ± 2.41ab 36.40 ± 8.43ab 0.32 ± 0.05a 38.13 ± 6.78a
5 d 12 5.65 ± 1.93ab 35.10 ± 8.44ab 0.29 ± 0.06ab 34.10 ± 6.23ab
7 d 10 4.98 ± 1.75ab 34.15 ± 8.30ab 0.29 ± 0.01ab 32.49 ± 6.61ab

BALF, bronchoalveolar lavage fluid; Control group, Sprague-Dawley rats were intraperitoneally injected with 1.25 ml/kg saline solution; PQ group, Sprague-Dawley rats were intraperitoneally injected with 15 ml/kg 2% paraquat solution; RAPA treatment group, paraquat-poisoned Sprague-Dawley rats were immediately intraperitoneally injected with 1.25 ml/kg saline solution containing 4 mg/kg rapamycin; 1 d, 3 d, 5 d, 7 d, 1, 3, 5, and 7 days after intraperitoneal injection;

a

compared with control group, P < 0.05;

ab

compared with PQ group, P < 0.05.